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Compound Susceptible To Oxidation-Reduction And Isoalloxazine Derivative
Novel FRET reagent

Field
Health Care, Chemistry
Keywords
Apoptosis, Cell Growth,  Cell Differentiation,  Isoalloxazine Derivatives, Firefly Luminescence, Oxidation-reduction


Abstracts
PROBLEM TO BE SOLVED: To provide a compound susceptible to oxidation-reduction and able to detect changes in oxidation-reduction potential in high sensitivity with time dependent analysis. ; SOLUTION: The compound has a first fluorochromophore in which a fluorescence spectrum reversibly varies with an oxidation-reduction reaction, a second fluorochromophore in which a fluorescent spectrum varies by mutual interaction with the first fluorophore and a linking group for linking the first fluorochromophore with the second fluorochromophore.

Advantages
According to this invention change of an oxidation-reduction potential high sensitivity and the oxidation reduction susceptibility compound which can be detected in time resolving can be provided.


Inventor
Prof. Shin Aoki et al. (Tokyo University of Science)


Patent Publication No
(APPLICATION NUMBER, FILING DATE)
JP2008-045051 (Feb.26, 2008)
(PUBLICATION NUMBER, PUBLICATION DATE)
JP, 2008-239615, A (Oct. 9, 2008)
(PRIORITY APPLICATION NUMBER, PRIORITY DATE)
JP2007-046172 (Feb. 26, 2007)   
 
Internal file number
T2007-120 (T2006-067)



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